(1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

Base Information

Chemical Name:(1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester
CAS No.:102267-38-9
Molecular Formula:C₁₆H₂₀O₃
Molecular Weight:260.333
Hs Code.:

Synonyms:(1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

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Chemical Property of (1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

Chemical Property:

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Technology Process of (1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

There total 3 articles about (1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 70871-15-7,71773-20-1
(1R,2R,3S)-4-Oxo-2-(3-phenyl-propyl)-cyclopentane-1,3-dicarboxylic acid dimethyl ester

: 102267-38-9
(1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

Guidance literature:: With sodium iodide; In diethylene glycol dimethyl ether; acetic acid; Heating;

Reference yield:

: 102267-17-4
5-Oxo-2-(3-phenyl-propyl)-cyclopent-1-ene-1,3-dicarboxylic acid dimethyl ester

: 102267-38-9
(1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / H₂ / 10 percent Pd-C / methanol / 0 °C

2: 85 percent / NaI / acetic acid; bis-(2-methoxy-ethyl) ether / Heating

With hydrogen; sodium iodide; palladium on activated charcoal; In methanol; diethylene glycol dimethyl ether; acetic acid;

Reference yield:

: 102267-10-7
4-Oxo-2-(4-phenyl-butyryl)-hexanedioic acid dimethyl ester

: 102267-38-9
(1S,2R)-4-Oxo-2-(3-phenyl-propyl)-cyclopentanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 71 percent / KHCO₃ / methanol / 30 - 40 °C

2: 75 percent / H₂ / 10 percent Pd-C / methanol / 0 °C

3: 85 percent / NaI / acetic acid; bis-(2-methoxy-ethyl) ether / Heating

With hydrogen; potassium hydrogencarbonate; sodium iodide; palladium on activated charcoal; In methanol; diethylene glycol dimethyl ether; acetic acid;