1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene

Base Information

• Chemical Name: 1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene
• CAS No.: 1149618-34-7
• Molecular Formula: C₂₀H₃₀O₅
• Molecular Weight: 350.455
• Mol file: 1149618-34-7.mol

Synonyms:1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene

Chemical Property of 1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene

Chemical Property:

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Technology Process of 1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene

There total 1 articles about 1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-bromobenzaldehyde diethyl acetal (34421-94-8) + 2-(3-Propinyloxy)-acetaldehyddiethylacetal (98166-29-1) → 1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene (1149618-34-7)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 50 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol9005689

Reference yield: 32.0%

1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene (1149618-34-7) → 4-(chloro(4-ethoxydihydrofuran-3(2H)-ylidene)methyl)benzaldehyde (1149618-51-8)

Guidance literature:

1-(3-(2,2-diethoxyethoxy)prop-1-ynyl)-4-diethoxymethylbenzene; With iron(III) chloride; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

With water; In dichloromethane; stereoselective reaction;

DOI:10.1021/ol9005689

upstream raw materials:

4-bromobenzaldehyde diethyl acetal

2-(3-Propinyloxy)-acetaldehyddiethylacetal

Downstream raw materials:

4-(chloro(4-ethoxydihydrofuran-3(2H)-ylidene)methyl)benzaldehyde