Technology Process of (+/-)-3-(4-methoxyphenyl)-4-methylpentanal
There total 6 articles about (+/-)-3-(4-methoxyphenyl)-4-methylpentanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
cis-chloromethyl[bis(dicyclohexylphosphino)ethane]palladium(II); sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate;
In
1,2-dichloro-ethane; cyclohexene;
at 20 - 85 ℃;
for 18h;
Inert atmosphere;
Sealed tube;
DOI:10.1021/ja508736u
- Guidance literature:
-
Multi-step reaction with 2 steps
1: LiAlH4 / diethyl ether / 0.08 h / 0 - 20 °C
2: (+/-)-1/[Rh(cod)2]BF4
With
lithium aluminium tetrahydride; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (+/-)-1;
In
diethyl ether;
DOI:10.1021/ja002471r
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: CuI; MeLi / tetrahydrofuran; diethyl ether; various solvent(s) / 3 h / -78 - 20 °C
1.2: 45 percent / tetrahydrofuran; diethyl ether; various solvent(s) / -78 - 20 °C
2.1: LiAlH4 / diethyl ether / 0.08 h / 0 - 20 °C
3.1: (+/-)-1/[Rh(cod)2]BF4
With
copper(l) iodide; lithium aluminium tetrahydride; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (+/-)-1; methyllithium;
In
tetrahydrofuran; diethyl ether;
DOI:10.1021/ja002471r
