methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

Base Information

Chemical Name:methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate
CAS No.:97227-64-0
Molecular Formula:C₂₃H₁₉NO₂
Molecular Weight:341.409
Hs Code.:
DSSTox Substance ID:DTXSID201228621

Synonyms:methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate;SCHEMBL10993388;FMODUECITYGBKK-UHFFFAOYSA-N;DTXSID201228621;97227-64-0

Suppliers and Price of methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:341.141578849
Heavy Atom Count:26
Complexity:479

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C(=C1C3=CC=CC=C3)C4=CC=C(C=C4)C(=O)OC

Technology Process of methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

There total 7 articles about methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 54655-08-2
N,N-dimethyl-2-(2-phenylethynyl)aniline

: 171364-80-0
methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

: 97227-64-0
methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

Guidance literature:: With palladium diacetate; copper(II) acetate monohydrate; In ethanol; at 74 ℃; for 12h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.8b02835

Reference yield:

: 948-65-2
2-phenyl-indole

: 97227-64-0
methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 44 percent / 85 percent H₃PO₄, AcOH, Ac₂O / 72 h / Ambient temperature

2: 71 percent / methanesulfonic acid / CH₂Cl₂ / 21 h / Heating

3: 1.) KOH / 1.) DMSO, 45 min, 2.) DMSO, RT, 3 h

4: DDQ / dioxane / 19 h / Heating

With potassium hydroxide; methanesulfonic acid; phosphoric acid; acetic anhydride; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm00380a002

Reference yield:

: 874-61-3
4-oxocyclohexanecarboxylic acid

: 97227-64-0
methyl 4-(1-methyl-2-phenyl-1H-indol-3-yl)benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 44 percent / 85 percent H₃PO₄, AcOH, Ac₂O / 72 h / Ambient temperature

2: 71 percent / methanesulfonic acid / CH₂Cl₂ / 21 h / Heating

3: 1.) KOH / 1.) DMSO, 45 min, 2.) DMSO, RT, 3 h

4: DDQ / dioxane / 19 h / Heating

With potassium hydroxide; methanesulfonic acid; phosphoric acid; acetic anhydride; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm00380a002