5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

Base Information

Chemical Name:5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine
CAS No.:76972-14-0
Molecular Formula:C₂₅H₃₀N₄O₄
Molecular Weight:450.538
Hs Code.:

Synonyms:5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

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Chemical Property of 5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

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Technology Process of 5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

There total 3 articles about 5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 76972-12-8
5-(3,4-dimethoxyphenyl)-2-(1-piperazinyl)pyrimidine

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 76972-14-0
5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 96h; under 2660 Torr;

Reference yield:

: 76972-10-6
2-chloro-5-(3,4-dimethoxyphenyl)pyrimidine

: 76972-14-0
5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / ethanol / 2 h / 60 °C

2: 73 percent / H₂ / palladium on carbon / methanol / 96 h / 2660 Torr

With hydrogen; palladium on activated charcoal; In methanol; ethanol;

Reference yield:

: 33266-39-6
5-(3,4-dimethoxy-phenyl)-1-methyl-1H-pyrimidin-2-one

: 76972-14-0
5-(3,4-dimethoxyphenyl)-2-<4-(3,4-dimethoxyphenyl)methyl>piperazinylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / phosphorus pentachloride, phosphorus oxychloride / 20 h / 120 °C

2: 89 percent / ethanol / 2 h / 60 °C

3: 73 percent / H₂ / palladium on carbon / methanol / 96 h / 2660 Torr

With phosphorus pentachloride; hydrogen; trichlorophosphate; palladium on activated charcoal; In methanol; ethanol;