Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Base Information

Chemical Name:Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester
CAS No.:114244-09-6
Molecular Formula:C₁₇H₂₀O₅
Molecular Weight:304.343
Hs Code.:

Synonyms:Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Suppliers and Price of Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

There total 10 articles about Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: Benzoic acid (1S,4S,4aS,6S,7R,7aR)-4-hydroxy-1-methoxy-7-methyl-octahydro-cyclopenta[c]pyran-6-yl ester

: 114244-09-6
Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Guidance literature:: With sodium acetate; pyridinium chlorochromate; In dichloromethane; Ambient temperature;
DOI:10.1039/C39870001002

Reference yield:

: (1S,2S,5R,6S)-5-Benzyloxy-2-methoxy-3,7-dioxa-bicyclo[4.1.0]heptane

: 114244-09-6
Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Guidance literature:: Multi-step reaction with 10 steps

1: 88 percent / diethyl ether / 0.5 h / Ambient temperature

2: 96 percent / imidazole / dimethylformamide / 30 °C

3: 1) O₃; 2) Et₃N / 1) CH₂Cl₂, -78 deg C; 2) RT, 4 h, CH₂Cl₂

4: 82 percent / tetrahydrofuran / 1.5 h / -78 °C

5: 91 percent / Et₃N, 4-N,N-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

6: 92 percent / n-Bu₄NF, NH₄Cl / tetrahydrofuran / 24 h / Ambient temperature

7: 100 percent / (Me₃Si)2NH, n-Buli / tetrahydrofuran / 15 h / Ambient temperature

8: 73 percent / n-Bu₃SnH, azoisobutyronitrile / benzene / 1 h / Heating

9: 85 percent / H₂ / Raney Ni / ethyl acetate / 5 h / Heating

10: 80 percent / pyridinium chlorochromtate, NaOAc / CH₂Cl₂ / Ambient temperature

With 1H-imidazole; dmap; n-butyllithium; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; hydrogen; tri-n-butyl-tin hydride; sodium acetate; ammonium chloride; ozone; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; pyridinium chlorochromate; nickel; In tetrahydrofuran; diethyl ether; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; benzene;
DOI:10.1039/C39870001002

Reference yield:

: 114217-63-9
(2S,3S,4S,5S)-4-Allyl-5-benzyloxy-2-methoxy-tetrahydro-pyran-3-ol

: 114244-09-6
Benzoic acid (1S,4aS,6S,7R,7aR)-1-methoxy-7-methyl-4-oxo-octahydro-cyclopenta[c]pyran-6-yl ester

Guidance literature:: Multi-step reaction with 9 steps

1: 96 percent / imidazole / dimethylformamide / 30 °C

2: 1) O₃; 2) Et₃N / 1) CH₂Cl₂, -78 deg C; 2) RT, 4 h, CH₂Cl₂

3: 82 percent / tetrahydrofuran / 1.5 h / -78 °C

4: 91 percent / Et₃N, 4-N,N-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

5: 92 percent / n-Bu₄NF, NH₄Cl / tetrahydrofuran / 24 h / Ambient temperature

6: 100 percent / (Me₃Si)2NH, n-Buli / tetrahydrofuran / 15 h / Ambient temperature

7: 73 percent / n-Bu₃SnH, azoisobutyronitrile / benzene / 1 h / Heating

8: 85 percent / H₂ / Raney Ni / ethyl acetate / 5 h / Heating

9: 80 percent / pyridinium chlorochromtate, NaOAc / CH₂Cl₂ / Ambient temperature

With 1H-imidazole; dmap; n-butyllithium; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; hydrogen; tri-n-butyl-tin hydride; sodium acetate; ammonium chloride; ozone; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; pyridinium chlorochromate; nickel; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; benzene;
DOI:10.1039/C39870001002