methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Base Information

Chemical Name:methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate
CAS No.:1607826-48-1
Molecular Formula:C₁₅H₁₉NO₆
Molecular Weight:309.319
Hs Code.:

Synonyms:methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Suppliers and Price of methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

There total 7 articles about methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 950839-11-9
methyl (2R,3R)-2-amino-3-(4-hydroxyphenyl)-3-methoxypropanoate

: 2937-50-0
Allyl chloroformate

: 1607826-48-1
methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; water; at 0 ℃; for 3h; Inert atmosphere;
DOI:10.1021/ja502744a

Reference yield:

: 1607826-46-9
methyl (2S,3R)-3-(4-(benzyloxy)phenyl)-3-hydroxy-2-(((2-nitrophenyl)sulfonyl)oxy)propanoate

: 1607826-48-1
methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium azide / N,N-dimethyl-formamide / 23 - 50 °C / Inert atmosphere

2: silver(l) oxide / dichloromethane / 50 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / dichloromethane / 23 °C / Inert atmosphere

4: sodium hydrogencarbonate / water; tetrahydrofuran / 3 h / 0 °C / Inert atmosphere

With sodium azide; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; silver(l) oxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja502744a

Reference yield:

: 1607826-45-8
methyl (2S,3R)-3-(4-(benzyloxy)phenyl)-2,3-dihydroxypropanoate

: 1607826-48-1
methyl (2R,3R)-2-(((allyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)-3-methoxypropanoate

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / dichloromethane / 6 h / 0 °C / Inert atmosphere

2: sodium azide / N,N-dimethyl-formamide / 23 - 50 °C / Inert atmosphere

3: silver(l) oxide / dichloromethane / 50 °C / Inert atmosphere

4: palladium 10% on activated carbon; hydrogen / dichloromethane / 23 °C / Inert atmosphere

5: sodium hydrogencarbonate / water; tetrahydrofuran / 3 h / 0 °C / Inert atmosphere

With sodium azide; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; triethylamine; silver(l) oxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja502744a