biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

Base Information

• Chemical Name: biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide
• CAS No.: 717855-07-7
• Molecular Formula: C₃₆H₃₈N₂O₅
• Molecular Weight: 578.708

Synonyms:biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

Chemical Property of biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

Chemical Property:

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Technology Process of biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

There total 1 articles about biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-acetyl-6-amino-5,7-dimethoxy-4-(4-methoxyphenyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline (717855-00-0) + 4-biphenyl-carboxylic acid chloride (14002-51-8) → biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide (717855-07-7)

Guidance literature:

With N,N-dimethyl-aniline; In dichloromethane; at 20 ℃;

Reference yield:

biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide (717855-07-7) → biphenyl-4-carboxylic acid [1-acetyl-5,7-dihydroxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

Guidance literature:

With boron tribromide; In dichloromethane; at 15 ℃;

Reference yield:

biphenyl-4-carboxylic acid [1-acetyl-5, 7-dimethoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide (717855-07-7) → biphenyl-4-carboxylic acid [1-acetyl-5-hydroxy-4-(4-hydroxy-phenyl)-7-methoxy-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide (717855-25-9)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 ℃;

upstream raw materials:

1-acetyl-6-amino-5,7-dimethoxy-4-(4-methoxyphenyl)-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline

4-biphenyl-carboxylic acid chloride

Downstream raw materials:

biphenyl-4-carboxylic acid [1-acetyl-5-hydroxy-7-methoxy-4-(4-methoxy-phenyl)-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

biphenyl-4-carboxylic acid [1-acetyl-5-hydroxy-4-(4-hydroxy-phenyl)-7-methoxy-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]amide

N-[1-acetyl-5-hydroxy-4-(4-hydroxy-phenyl)-7-methoxy-2, 2,4-trimethyl-1,2,3, 4-tetrahydroquinoline-6-yl]-3,5-dichlorobenzamide

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