methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Base Information

Chemical Name:methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside
CAS No.:1394848-33-9
Molecular Formula:C₂₉H₂₉NO₆
Molecular Weight:487.552
Hs Code.:

Synonyms:methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Suppliers and Price of methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

There total 3 articles about methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 136918-14-4,85-41-6
phthalimide

: 1394848-29-3
methyl 3,5-di-O-benzyl-2-deoxy-2-α-hydroxymethyl-α-D-ribofuranoside

: 1394848-33-9
methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1039/c2cc34556k

Reference yield:

: 885592-69-8
(2S,4R,5R)-4-(benzyloxy)-5-((benzyloxy)methyl)-2-methoxydihydrofuran-3(2H)-one

: 1394848-33-9
methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: sec.-butyllithium / tetrahydrofuran; cyclohexane / 1 h / -78 °C / Inert atmosphere

1.2: 72 h / -78 - 20 °C / Inert atmosphere

2.1: 9-borabicyclo[3.3.1]nonane dimer / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere

2.2: 2 h / 20 °C

3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

With 9-borabicyclo[3.3.1]nonane dimer; sec.-butyllithium; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; cyclohexane; 1.2: Wittig reaction / 2.1: Hydroboration reaction / 3.1: Mitsunobu reaction;
DOI:10.1039/c2cc34556k

Reference yield:

: 1394848-32-8
methyl 3,5-di-O-benzyl-2-methylene-α-D-ribofuranoside

: 1394848-33-9
methyl 3,5-di-O-benzyl-2-deoxy-2-α-phthalimidomethyl-α-D-ribofuranoside

Guidance literature:: Multi-step reaction with 2 steps

1.1: 9-borabicyclo[3.3.1]nonane dimer / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere

1.2: 2 h / 20 °C

2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

With 9-borabicyclo[3.3.1]nonane dimer; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1.1: Hydroboration reaction / 2.1: Mitsunobu reaction;
DOI:10.1039/c2cc34556k