diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate

Base Information

• Chemical Name: diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate
• CAS No.: 288403-50-9
• Molecular Formula: C₁₀₈H₁₆₂FN₂O₁₇P
• Molecular Weight: 1810.45
• Mol file: 288403-50-9.mol

Synonyms:diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate

Chemical Property of diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate

There total 1 articles about diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C106H160FN2O16P + acetic anhydride (108-24-7) → diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate (288403-50-9)

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/S0008-6215(01)00134-3

Reference yield: 80.0%

diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate (288403-50-9) → 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(hydroxy)tetradecanamido]-4-O-[(R)-3-(hydroxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonic acid

Guidance literature:

With hydrogen; palladium hydroxide - carbon; In ethanol; at 20 ℃; for 18h;

DOI:10.1016/S0008-6215(01)00134-3

Reference yield:

diphenylmethyl 2,6-anhydro-7-O-[2-acetamido-2,6-dideoxy-4-O-(diphenylphosphono)-3-O-[(R)-3-(dodecyloxy)tetradecyl]-6-fluoro-β-D-glucopyranosyl]-3-[(R)-3-(benzyloxy)tetradecanamido]-4-O-[(R)-3-(benzyloxy)tetradecyl]-3-deoxy-D-glycero-D-ido-heptonate (288403-50-9) → C106H160FN2O16P

Guidance literature:

With acetic acid; zinc; at 20 ℃; for 5h;

DOI:10.1016/S0008-6215(01)00134-3

upstream raw materials:

acetic anhydride