2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Base Information

Chemical Name:2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide
CAS No.:872984-01-5
Molecular Formula:C₃₉H₄₉N₃O₃Si
Molecular Weight:635.922
Hs Code.:

2-(2-amino-3-phenyl-propionylamino)-2-[2-(<i>tert</i>-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Synonyms:2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Suppliers and Price of 2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

There total 8 articles about 2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 872983-45-4
((1S)-1-{1-benzylcarbamoyl-1-[2-(tert-butyldiphenylsiloxy)ethyl]butylcarbamoyl}-2-phenylethyl)carbamic acid benzyl ester

: 872984-01-5
2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃;
DOI:10.1016/j.bmc.2005.08.019

Reference yield:

: 872983-41-0
3-amino-3-propyldihydrofuran-2-one

: 872984-01-5
2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Guidance literature:: Multi-step reaction with 5 steps

1: 1.8 g / 2-phenylbenzoxazole; ethyldiisopropylamine / CH₂Cl₂ / 0 °C

2: 1.8 g / lithium hydroxide / tetrahydrofuran; H₂O / 0 °C

3: 1.66 g / imidazole / CH₂Cl₂ / 0 °C

4: 1.5 g / 1-hydroxy-1H-benzotriazole; 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide HCl; triethylamine / CH₂Cl₂ / 0 °C

5: 100 percent / H₂ / Pd-C / methanol / 20 °C

With 1H-imidazole; lithium hydroxide; 2-phenylbenzo[d]oxazole; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1016/j.bmc.2005.08.019

Reference yield:

: 2-amino-2-(2-hydroxy-ethyl)-pentanoic acid

: 872984-01-5
2-(2-amino-3-phenyl-propionylamino)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-pentanoic acid benzylamide

Guidance literature:: Multi-step reaction with 6 steps

1: 2.4 g / hydrochloric acid / 16 h / Heating

2: 1.8 g / 2-phenylbenzoxazole; ethyldiisopropylamine / CH₂Cl₂ / 0 °C

3: 1.8 g / lithium hydroxide / tetrahydrofuran; H₂O / 0 °C

4: 1.66 g / imidazole / CH₂Cl₂ / 0 °C

5: 1.5 g / 1-hydroxy-1H-benzotriazole; 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide HCl; triethylamine / CH₂Cl₂ / 0 °C

6: 100 percent / H₂ / Pd-C / methanol / 20 °C

With 1H-imidazole; hydrogenchloride; lithium hydroxide; 2-phenylbenzo[d]oxazole; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1016/j.bmc.2005.08.019