2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride

Base Information

• Chemical Name: 2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride
• CAS No.: 83256-51-3
• Molecular Formula: C₂₄H₁₉N₃O₂*ClH
• Molecular Weight: 417.895
• Mol file: 83256-51-3.mol

Synonyms:2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride

Chemical Property of 2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride

There total 1 articles about 2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

N-phthalyl-β-phenyl-β-alanine N'-methyl-N'-phenylhydrazide (83256-53-5) → 13-oxo-6-methyl-11-phenyl-11,12a-dihydro-13H-isoindolo<1',2':2,3>pyrimido<5,6-b>indole (83256-49-9) + 2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride (83256-51-3)

Guidance literature:

With trichlorophosphate; In dichloromethane; for 25h; Heating;

DOI:10.1007/BF00568946

Reference yield:

2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride (83256-51-3) → benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / Heating

2: 13 percent / conc. HCl / ethanol / 10 h / Heating

With hydrogenchloride; In ethanol; benzene;

DOI:10.1007/BF00568946

Reference yield:

2-amino-1-methyl-3-(α-phenylphthalimidomethyl)indole hydrochloride (83256-51-3) → 2-imino-1-methyl-3-benzylideneindoline hydrochloride (76950-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / Heating

2: 65 percent / conc. HCl / ethanol / 10 h / Heating

With hydrogenchloride; In ethanol; benzene;

DOI:10.1007/BF00568946

upstream raw materials:

N-phthalyl-β-phenyl-β-alanine N'-methyl-N'-phenylhydrazide

Downstream raw materials:

13-oxo-6-methyl-11-phenyl-11,12a-dihydro-13H-isoindolo<1',2':2,3>pyrimido<5,6-b>indole

2-imino-1-methyl-3-benzylideneindoline hydrochloride

benzene-1,2-dicarboxylic acid

5,7-dimethyl-12-phenylindolo<2,3-b;3',2'-e>pyridine