ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate

Base Information

Chemical Name:ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate
CAS No.:1263054-47-2
Molecular Formula:C₂₆H₃₁NO₃
Molecular Weight:405.537
Hs Code.:

Synonyms:ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate

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Chemical Property of ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate

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Technology Process of ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate

There total 1 articles about ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 461641-15-6
5-isopropyl-4-phenyl-1,9,9a,10a-tetrahydro-4H,4bH-10-oxa-4a-aza-indeno[1,2-a]indene-2-carboxylic acid ethyl ester

: 1263054-47-2
ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate

Guidance literature:: With sodium tetrahydroborate; boron trifluoride diethyl etherate; In tetrahydrofuran; at 0 ℃; for 0.5h;
DOI:10.1039/c0ob00627k

Reference yield:

: 1263054-47-2
ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate

: 925-90-6
ethylmagnesium bromide

: C₂₈H₃₇NO₃

: C₂₈H₃₇NO₃

Guidance literature:: ethyl (2S)-1-[(1S,2R)-2-hydroxyl-7-isopropylindan-1-yl]-2-phenyl-1,2,5,6-tetrahydropyridine-4-carboxylate; ethylmagnesium bromide; In diethyl ether; at 0 ℃;

With hydrogenchloride; In diethyl ether; water; optical yield given as %de;
DOI:10.1039/c0ob00627k