3,5-di-tert-butylsalicylic acid chloride

Base Information

• Chemical Name: 3,5-di-tert-butylsalicylic acid chloride
• CAS No.: 25130-85-2
• Molecular Formula: C₁₅H₂₁ClO₂
• Molecular Weight: 268.784
• Mol file: 25130-85-2.mol

Synonyms:3,5-di-tert-butylsalicylic acid chloride

Chemical Property of 3,5-di-tert-butylsalicylic acid chloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3,5-di-tert-butylsalicylic acid chloride

There total 1 articles about 3,5-di-tert-butylsalicylic acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-ditertbutyl salicylic acid (19715-19-6) → 3,5-di-tert-butylsalicylic acid chloride (25130-85-2)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; In benzene; at 60 ℃; for 1h;

DOI:10.1021/jm9803572

Reference yield: 95.0%

3-amino-4-hydroxybenzonitrile (14543-43-2) + 3,5-di-tert-butylsalicylic acid chloride (25130-85-2) → 3,5-di-tert-butyl-N-(5-cyano-2-hydroxy-phenyl)-2-hydroxy-benzamide (357156-65-1)

Guidance literature:

In 1,4-dioxane; at 100 ℃;

DOI:10.1016/S0960-894X(01)00024-5

Reference yield: 78.0%

pyridine-2-carboxylic acid (2-amino-phenyl)-amide (90209-81-7) + 3,5-di-tert-butylsalicylic acid chloride (25130-85-2) → NC5H4C(O)NHC6H4NHC(O)C6H2(C(CH3)3)2OH (1021875-93-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.jorganchem.2008.01.009

upstream raw materials:

3,5-ditertbutyl salicylic acid

Downstream raw materials:

3,5-di-tert-butyl-N-(5-cyano-2-hydroxy-phenyl)-2-hydroxy-benzamide

1,2-bis-(3,5-di-tert-butyl-2-hydroxybenzamido)benzene

NC₅H₄C(O)NHC₆H₄NHC(O)C₆H₂(C(CH₃)3)2OH

3,5-di-tert-butyl-2-hydroxy-N,N-dimethylbenzamide