1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

Base Information

Chemical Name:1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine
CAS No.:1382358-19-1
Molecular Formula:C₂₃H₁₉FIN₃O₆
Molecular Weight:579.323
Hs Code.:

Synonyms:1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of 1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

There total 4 articles about 1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22224-41-5
1,3,5-tri-O-benzoyl-α-D-ribofuranoside

: 1382358-19-1
1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

Guidance literature:: Multi-step reaction with 4 steps

1: diethylamino-sulfur trifluoride

2: hydrogen bromide; acetic acid

3: 1,2-dichloro-ethane / 48 h / 20 °C / Inert atmosphere

4: methanol / dichloromethane; 1,2-dichloro-ethane

With methanol; diethylamino-sulfur trifluoride; hydrogen bromide; acetic acid; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/j.tet.2012.04.031

Reference yield:

: C₂₉H₃₅FIN₃O₆Si₂

: 1382358-19-1
1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

Guidance literature:: With methanol; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/j.tet.2012.04.031

Reference yield:

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 1382358-19-1
1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-β-D-arabinofuranosyl)-5-iodocytosine

Guidance literature:: Multi-step reaction with 2 steps

1: 1,2-dichloro-ethane / 48 h / 20 °C / Inert atmosphere

2: methanol / dichloromethane; 1,2-dichloro-ethane

With methanol; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/j.tet.2012.04.031