pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Base Information

Chemical Name:pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate
CAS No.:154627-60-8
Molecular Formula:C₂₂H₂₀F₅NO₆
Molecular Weight:489.396
Hs Code.:

Synonyms:pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Suppliers and Price of pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

There total 5 articles about pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 154627-63-1
5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylic acid

: 154627-60-8
pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; at -20 - 20 ℃; for 16h;
DOI:10.1039/c39920001186

Reference yield:

: 51430-71-8
2-phenyl-5-(hydroxymethyl)-5-nitro-1,3-dioxane

: 154627-60-8
pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / H₂, Et₃N / Pd-C / ethanol / 72 h / 22501.8 Torr / Ambient temperature

2: 99 percent / CH₂Cl₂ / 14 h / Ambient temperature

3: 95 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂ / 1.) -60 deg C, 30 min, 2.) -60 deg C to room temp., 40 min

4: 72 percent / H₂NSO₃H, NaClO₂, Na₂HPO₄ / dioxane; H₂O / 1.) 5 deg C, 10 min, 2.) room temp., 30 min

5: 99 percent / dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH₂Cl₂ / 16 h / -20 - 20 °C

With dmap; sodium chlorite; disodium hydrogenphosphate; oxalyl dichloride; aminosulfonic acid; hydrogen; dimethyl sulfoxide; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In 1,4-dioxane; ethanol; dichloromethane; water;
DOI:10.1055/s-1993-25948

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 154627-60-8
pentafluorophenyl 5-tert-butoxycarbonylamino-2-phenyl-1,3-dioxane-5-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / CH₂Cl₂ / 14 h / Ambient temperature

2: 95 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂ / 1.) -60 deg C, 30 min, 2.) -60 deg C to room temp., 40 min

3: 72 percent / H₂NSO₃H, NaClO₂, Na₂HPO₄ / dioxane; H₂O / 1.) 5 deg C, 10 min, 2.) room temp., 30 min

4: 99 percent / dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH₂Cl₂ / 16 h / -20 - 20 °C

With dmap; sodium chlorite; disodium hydrogenphosphate; oxalyl dichloride; aminosulfonic acid; dimethyl sulfoxide; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane; water;
DOI:10.1055/s-1993-25948