(N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine

Base Information

• Chemical Name: (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine
• CAS No.: 258885-11-9
• Molecular Formula: C₃₁H₄₄N₃P
• Molecular Weight: 489.684
• Mol file: 258885-11-9.mol

Synonyms:(N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine

Chemical Property of (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine

There total 4 articles about (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + N-(4-bromo-benzyl)-N-(2-diethylamino-ethyl)-N',N'-diethyl-ethane-1,2-diamine (258885-10-8) → (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine (258885-11-9)

Guidance literature:

N-(4-bromo-benzyl)-N-(2-diethylamino-ethyl)-N',N'-diethyl-ethane-1,2-diamine; With iodine; magnesium; In tetrahydrofuran;

chloro-diphenylphosphine; In tetrahydrofuran;

DOI:10.1039/a908077e

Reference yield: 72.0%

N,N,N',N'-tetraethyldiethylenetriamine (123-12-6) + 4-(diphenylphosphino)benzaldehyde (5068-18-8) → (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine (258885-11-9)

Guidance literature:

With sodium cyanoborohydride; In methanol; at 20 ℃; for 16h;

DOI:10.1039/a908077e

Reference yield:

N,N,N',N'-tetraethyldiethylenetriamine (123-12-6) → (N-bis(N',N'-diethyl-2-aminoethyl)-4-aminomethylphenyl)diphenylphosphine (258885-11-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 84 percent / ethanol / 2 h / Heating

2.1: magnesium; I₂ / tetrahydrofuran

2.2: 82 percent / tetrahydrofuran

With iodine; magnesium; In tetrahydrofuran; ethanol; 1.1: Substitution / 2.1: Grignard reaction / 2.2: Substitution;

DOI:10.1039/a908077e

upstream raw materials:

N,N,N',N'-tetraethyldiethylenetriamine

4-(diphenylphosphino)benzaldehyde

chloro-diphenylphosphine

N-(4-bromo-benzyl)-N-(2-diethylamino-ethyl)-N',N'-diethyl-ethane-1,2-diamine

Downstream raw materials:

PtCl₂(C₃₁H₄₄N₃P)2