C₃₃H₅₀O₃Si₂

Base Information

• Chemical Name: C₃₃H₅₀O₃Si₂
• CAS No.: 1255639-76-9
• Molecular Formula: C₃₃H₅₀O₃Si₂
• Molecular Weight: 550.929
• Mol file: 1255639-76-9.mol

Synonyms:C₃₃H₅₀O₃Si₂

Chemical Property of C₃₃H₅₀O₃Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₅₀O₃Si₂

There total 4 articles about C₃₃H₅₀O₃Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(R)-triethyl(pent-4-yn-2-yloxy)silane (1255639-75-8) + C22H28O2Si (1255639-74-7) → C33H50O3Si2 (1255639-76-9)

Guidance literature:

(R)-triethyl(pent-4-yn-2-yloxy)silane; With n-butyllithium; In tetrahydrofuran; at -78 - -10 ℃; Inert atmosphere;

C₂₂H₂₈O₂Si; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ml1001807

Reference yield:

(S)-3-(tert-butyldiphenylsiloxy)hex-5-en-1-ol (1255639-73-6) → C33H50O3Si2 (1255639-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / -78 - -10 °C / Inert atmosphere

2.2: -78 - 20 °C / Inert atmosphere

With n-butyllithium; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane; 1.1: Swern oxidation / 1.2: Swern oxidation;

DOI:10.1021/ml1001807

Reference yield:

(S)-1-(tert-butyldimethylsiloxy)-3-(tert-butyldiphenylsiloxy)hex-5-ene (1255639-72-5) → C33H50O3Si2 (1255639-76-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: water; toluene-4-sulfonic acid / tetrahydrofuran / 10 h / 20 °C / Inert atmosphere

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere

2.2: -78 - 20 °C / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran / -78 - -10 °C / Inert atmosphere

3.2: -78 - 20 °C / Inert atmosphere

With n-butyllithium; oxalyl dichloride; water; toluene-4-sulfonic acid; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane; 2.1: Swern oxidation / 2.2: Swern oxidation;

DOI:10.1021/ml1001807

upstream raw materials:

(S)-1-(tert-butyldimethylsiloxy)-3-(tert-butyldiphenylsiloxy)hex-5-ene

(S)-3-(tert-butyldiphenylsiloxy)hex-5-en-1-ol

(R)-triethyl(pent-4-yn-2-yloxy)silane

C₂₂H₂₈O₂Si

Downstream raw materials:

C₄₈H₇₄O₇Si₃

C₄₈H₇₆O₇Si₃

C₄₁H₅₈O₆Si₂

C₃₅H₄₂O₆Si