2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine

Base Information

Chemical Name:2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine
CAS No.:95426-76-9
Molecular Formula:C₁₈H₂₀N₂O₂
Molecular Weight:296.369
Hs Code.:
European Community (EC) Number:635-550-6

Synonyms:2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine;95426-76-9;2-[2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]ethylamine;SCHEMBL7997254;DVZWARAGEKCJTH-UHFFFAOYSA-N;AKOS024324319;3-(2-aminoethyl)-2-(3,4-dimethoxyphenyl)indole;2-[2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]-ethylamine;2-[2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]ethan-1-amine

Suppliers and Price of 2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
3-(2-AMINOETHYL)-2-(3,4-DIMETHOXYPHENYL)INDOLE AldrichCPR
50mg
$ 57.00

Total 4 raw suppliers

Chemical Property of 2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:296.152477885
Heavy Atom Count:22
Complexity:352

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(2-AMINOETHYL)-2-(3,4-DIMETHOXYPHENYL)INDOLE AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2=C(C3=CC=CC=C3N2)CCN)OC

Technology Process of 2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine

There total 6 articles about 2-(2-(3,4-Dimethoxyphenyl)-1H-indol-3-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61-54-1
tryptamine

: 95426-76-9
2-[2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]-ethylamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: toluene / 13 h / Reflux

2.1: pyridinium hydrobromide perbromide / chloroform; tetrahydrofuran / 1 h / -10 °C

3.1: sodium carbonate monohydrate; lithium chloride / ethanol; water; toluene / 0.5 h / Inert atmosphere

3.2: 6 h / Inert atmosphere; Reflux

4.1: hydrazine hydrate / dichloromethane; methanol / 16 h / Reflux

With pyridinium hydrobromide perbromide; sodium carbonate monohydrate; hydrazine hydrate; lithium chloride; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water; toluene;
DOI:10.1021/ol501409a

Reference yield:

: 1616348-02-7
2-(2-(2-(3,4-dimethoxyphenyl)-1H-indol-3-yl)ethyl)isoindoline-1,3-dione

: 95426-76-9
2-[2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]-ethylamine

Guidance literature:: With hydrazine hydrate; In methanol; dichloromethane; for 16h; Reflux;
DOI:10.1021/ol501409a

Reference yield:

: 15741-71-6
N-phthalimidotryptamine

: 95426-76-9
2-[2-(3,4-dimethoxyphenyl)-1H-indol-3-yl]-ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridinium hydrobromide perbromide / chloroform; tetrahydrofuran / 1 h / -10 °C

2.1: sodium carbonate monohydrate; lithium chloride / ethanol; water; toluene / 0.5 h / Inert atmosphere

2.2: 6 h / Inert atmosphere; Reflux

3.1: hydrazine hydrate / dichloromethane; methanol / 16 h / Reflux

With pyridinium hydrobromide perbromide; sodium carbonate monohydrate; hydrazine hydrate; lithium chloride; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; water; toluene;
DOI:10.1021/ol501409a