3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane

Base Information

• Chemical Name: 3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane
• CAS No.: 1061288-64-9
• Molecular Formula: C₂₆H₃₀N₂O₂
• Molecular Weight: 402.536
• Mol file: 1061288-64-9.mol

Synonyms:3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane

Chemical Property of 3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane

There total 1 articles about 3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

4-methoxyphenylacetone oxime (52271-41-7) + RTI-32 (130342-81-3) → 3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane (1061288-64-9) + 3β-(4-methylphenyl)-2β-[3'-methyl-4'-(4-methoxyphenyl)isoxazol-5-yl]tropane (1061288-84-3)

Guidance literature:

4-methoxyphenylacetone oxime; With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 70 ℃;

RTI-32; In tetrahydrofuran; hexane; for 3h; Heating;

With hydrogenchloride; In tetrahydrofuran; for 5h; Further stages.; Heating;

DOI:10.1016/j.bmc.2008.05.073

upstream raw materials:

4-methoxyphenylacetone oxime

RTI-32