(S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane

Base Information

• Chemical Name: (S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane
• CAS No.: 745828-49-3
• Molecular Formula: C₃₆H₃₄O₂Si₂
• Molecular Weight: 554.836
• Mol file: 745828-49-3.mol

Synonyms:(S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane

Chemical Property of (S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane

There total 2 articles about (S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

(R)-fluoro(4-methoxynaphth-1-yl)methylphenylsilane (745828-47-1) → (S,R)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane + (S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane (745828-49-3)

Guidance literature:

With (trimethylstannyl)lithium; In tetrahydrofuran; at -78 ℃;

With methyllithium; In tetrahydrofuran; at -78 ℃;

(R)-fluoro(4-methoxynaphth-1-yl)methylphenylsilane; In tetrahydrofuran; at -78 ℃; for 0.5h;

DOI:10.1021/jo049398y

Reference yield:

(S)-(-)-[(-)-menthoxy](4-methoxynaphth-1-yl)methylphenylsilane → (S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane (745828-49-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: BF₃*Et₂O / diethyl ether; toluene / 168 h / 50 °C

2.1: Me₃SnLi / tetrahydrofuran / -78 °C

2.2: MeLi / tetrahydrofuran / -78 °C

2.3: 43 percent / tetrahydrofuran / 0.5 h / -78 °C

With (trimethylstannyl)lithium; boron trifluoride diethyl etherate; In tetrahydrofuran; diethyl ether; toluene;

DOI:10.1021/jo049398y

Reference yield:

(S,S)-1,2-dimethyl-1,2-di(4-methoxynaphth-1-yl)-1,2-diphenyldisilane (745828-49-3) → 1,2-dibromo-1,2-dimethyl-1,2-diphenyl-disilane

Guidance literature:

With bromine; In chloroform; at -64 ℃;

DOI:10.1021/jo049398y

upstream raw materials:

(R)-fluoro(4-methoxynaphth-1-yl)methylphenylsilane

Downstream raw materials:

1,2-dimethyl-1,2-diphenyldisilane