methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate

Base Information

Chemical Name:methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate
CAS No.:947756-94-7
Molecular Formula:C₂₈H₃₂N₄O₆S
Molecular Weight:552.651
Hs Code.:

Synonyms:methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate

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Chemical Property of methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate

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Technology Process of methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate

There total 1 articles about methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 335255-30-6
(2-amino-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester

: 947756-93-6
4-[2-methoxy-1-({[(methylamino)carbonyl]amino}methyl)-2-oxoethyl]benzoic acid

: 947756-94-7
methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate

Guidance literature:: 4-[2-methoxy-1-({[(methylamino)carbonyl]amino}methyl)-2-oxoethyl]benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 0.166667h;

(2-amino-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester; In N,N-dimethyl-formamide; at 55 ℃; for 24h;

Reference yield:

: 947756-94-7
methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate

: 947756-95-8
2-[4-({[2-[(tert-Butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)-phenyl]-3-{[(methyl-amino)carbonyl]amino}propanoic acid

Guidance literature:: methyl 2-[4-({[2-[(tert-butoxycarbonyl)amino]-5-(3-thienyl)phenyl]amino}carbonyl)phenyl]-3-{[(methylamino)carbonyl]amino}propanoate; With potassium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

With citric acid; In tetrahydrofuran; methanol;