4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate

Base Information

• Chemical Name: 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate
• CAS No.: 1071193-33-3
• Molecular Formula: C₁₂H₁₄F₃NO₅S
• Molecular Weight: 341.308
• Mol file: 1071193-33-3.mol

Synonyms:4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate

Chemical Property of 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate

There total 1 articles about 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

trifluoromethylsulfonic anhydride (358-23-6) + 4-hydroxyphenyl diethylcarbamate → 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate (1071193-33-3)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1055/s-0037-1611053

Reference yield: 89.0%

4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate (1071193-33-3) + 3,4-(methylenedioxy)-benzeneboronic acid (94839-07-3) → 4-[3,4-(methylenedioxy)phenyl]phenyl diethylcarbamate

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; ethanol; for 24h; Reflux;

DOI:10.1055/s-0037-1611053

Reference yield: 85.0%

1,2-(methylenedioxy)-4-bromobenzene (2635-13-4) + 4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate (1071193-33-3) → 4-[3,4-(methylenedioxy)phenyl]phenyl diethylcarbamate

Guidance literature:

1,2-(methylenedioxy)-4-bromobenzene; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 0.25h; Inert atmosphere;

With zinc(II) chloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

4-(trifluoromethylsulfonyloxy)phenyl diethylcarbamate; With bis(acetylacetonate)nickel(II); methylmagnesium bromide; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 30h; Reagent/catalyst; Inert atmosphere;

DOI:10.1055/s-0037-1611053

upstream raw materials:

trifluoromethylsulfonic anhydride

Downstream raw materials:

4-hydroxyphenyl trifluoromethanesulfonate