2-Acetylaminocarbazole

Base Information

• Chemical Name: 2-Acetylaminocarbazole
• CAS No.: 63020-20-2
• Molecular Formula: C14H12N2O
• Molecular Weight: 224.26
• DSSTox Substance ID: DTXSID20877418
• Nikkaji Number: J524.453F
• Wikidata: Q82859214
• ChEMBL ID: CHEMBL63669
• Mol file: 63020-20-2.mol

Synonyms:2-Acetylaminocarbazole;63020-20-2;CHEMBL63669;CCRIS 6505;N-9H-Carbazol-2-ylacetamide;Acetamide, N-9H-carbazol-2-yl-;BRN 0384208;ACETAMIDE,N-9H-CARBAZOL-2-YL-;N-2-Carbazolylacetamide;2-ACETAMIDOCARBAZOLE;Acetamide, N-2-carbazolyl-;4-22-00-04934 (Beilstein Handbook Reference);NIOSH/AB5004910;SCHEMBL22616930;DTXSID20877418;N-(9H-Carbazol-2-yl)-acetamide;BDBM50038944;AB50049100

Chemical Property of 2-Acetylaminocarbazole

Chemical Property:

• Vapor Pressure: 1.63E-11mmHg at 25°C
• Melting Point: 237-238 °C
• Boiling Point: 534.8°C at 760 mmHg
• PKA: 15.67±0.43(Predicted)
• Flash Point: 277.2°C
• PSA: 44.89000
• Density: 1.326g/cm³
• LogP: 3.35250
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 224.094963011
• Heavy Atom Count: 17
• Complexity: 305

Purity/Quality:

98.5% ^*data from raw suppliers

2-ACETYLAMINOCARBAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3N2

Technology Process of 2-Acetylaminocarbazole

There total 20 articles about 2-Acetylaminocarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-(2-nitro-biphenyl-4-yl)-acetamide → N-(9H-carbazol-2-yl)acetamide (63020-20-2)

Guidance literature:

With 1,10-Phenanthroline; carbon monoxide; palladium diacetate; In N,N-dimethyl-formamide; at 140 ℃; for 16h; under 3102.89 Torr;

DOI:10.1021/ol036294l

Reference yield: 77.0%

2-acetylamino-9-acetylcarbazole (77229-05-1) → N-(9H-carbazol-2-yl)acetamide (63020-20-2)

Guidance literature:

With potassium hydroxide; In methanol; for 0.0833333h;

DOI:10.1016/0040-4020(80)88027-6

Reference yield: 58.0%

2-acetylcarbazole oxime (77229-01-7) → N-(9H-carbazol-2-yl)acetamide (63020-20-2)

Guidance literature:

With phosphorus pentachloride; In tetrahydrofuran; for 1h; Ambient temperature;

DOI:10.1016/0040-4020(80)88027-6

upstream raw materials:

2-aminocarbazole

acetic anhydride

2-acetylcarbazole oxime

2-acetylamino-9-acetylcarbazole