4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide

Base Information

Chemical Name:4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide
CAS No.:863646-41-7
Molecular Formula:C₁₁H₁₇N₃O₂
Molecular Weight:223.275
Hs Code.:
DSSTox Substance ID:DTXSID101233174

Synonyms:4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide;SCHEMBL5479330;YQSKJBOZCNDFOA-UHFFFAOYSA-N;DTXSID101233174;AKOS000130270;863646-41-7;4-[2-(Dimethylamino)ethoxy]benzoic acid hydrazide

Suppliers and Price of 4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:223.132076794
Heavy Atom Count:16
Complexity:213

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CCOC1=CC=C(C=C1)C(=O)NN

Technology Process of 4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide

There total 4 articles about 4-(2-Dimethylamino-ethoxy)-benzoic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.9%

: 25773-00-6
ethyl 4-(dimethylaminoethoxy)benzoate

: 863646-41-7
N'-benzylidene-4-(2-(dimethylamino)ethoxy)benzohydrazide

Guidance literature:: With hydrazine; In ethanol; at 100 ℃;

Reference yield:

: 73119-82-1
methyl 4-<2-(dimethylamino)ethoxy>benzoate

: 863646-41-7
N'-benzylidene-4-(2-(dimethylamino)ethoxy)benzohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; for 6h; Reflux;
DOI:10.1016/j.ejmech.2016.08.022

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 863646-41-7
N'-benzylidene-4-(2-(dimethylamino)ethoxy)benzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / Reflux

1.2: 50 h / Reflux

2.1: hydrazine hydrate / ethanol / 6 h / Reflux

With hydrazine hydrate; potassium tert-butylate; In tetrahydrofuran; ethanol;
DOI:10.1016/j.ejmech.2016.08.022