(S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
CAS No.:1418307-18-2
Molecular Formula:C₁₈H₁₇ClN₄O₂
Molecular Weight:356.812
Hs Code.:
Mol file:1418307-18-2.mol

Synonyms:(S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid benzyl ester

Suppliers and Price of (S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
benzyl(2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate 95%+
1g
$ 1342.00

Chemenu
benzyl(2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate 95%+
250mg
$ 429.00

Chemenu
benzyl(2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate 95%+
100mg
$ 322.00

Total 14 raw suppliers

Chemical Property of (S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

Chemical Property:

PKA:3?+-.0.30(Predicted)
Density:1.41±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

benzyl(2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

There total 7 articles about (S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1418307-17-1
benzyl (S)-2-(((3-chloropyrazin-2-yl)methyl)carbamoyl)pyrrolidine-1-carboxylate

: 1418307-18-2
(S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid benzyl ester

Guidance literature:: With 1,3-dimethyl-2-imidazolidinone; trichlorophosphate; In acetonitrile; at 0 - 65 ℃;

Reference yield:

: C₁₈H₁₉ClN₄O₃

: 1418307-18-2
(S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid benzyl ester

Guidance literature:: C₁₈H₁₉ClN₄O₃; In acetonitrile; at 5 ℃; for 0.5h;

With trichlorophosphate; In acetonitrile; at 70 ℃; for 20h;

Reference yield:

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 1418307-18-2
(S)-2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 0.25 h / 0 °C

1.2: 0 - 20 °C

2.1: 1,3-dimethyl-2-imidazolidinone; trichlorophosphate / acetonitrile / 0 - 65 °C

With 1,3-dimethyl-2-imidazolidinone; triethylamine; trichlorophosphate; In dichloromethane; acetonitrile;