(S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide

Base Information

• Chemical Name: (S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide
• CAS No.: 106637-04-1
• Molecular Formula: C₂₃H₃₄N₂O₃
• Molecular Weight: 386.535
• Mol file: 106637-04-1.mol

Synonyms:(S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide

Chemical Property of (S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide

There total 1 articles about (S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

L-menthylamine (2216-54-8,787534-09-2) + N-Benzyloxycarbonyl-L-proline (1148-11-4) → (S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide (106637-04-1)

Guidance literature:

With 4-methyl-morpholine; chloroformic acid ethyl ester; In ethyl acetate; 1.) -15 deg C, 1 h, 2.) room temp.;

Reference yield: 78.0%

(S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide (106637-04-1) → (S)-Proline (R)-menthylamide (106637-05-2)

Guidance literature:

With cyclohexene; palladium on activated charcoal; In methanol; for 3h; Heating;

Reference yield:

(S)-N-(Benzyloxycarbonyl)proline (R)-menthylamide (106637-04-1) → L-menthylamine (2216-54-8,787534-09-2) + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7)

Guidance literature:

With potassium hydroxide; cyclohexene; palladium on activated charcoal; Product distribution; 1.) H₂O/EtOH, reflux, 8 h, 2.) benzene, reflux, 2 h;

upstream raw materials:

L-menthylamine

N-Benzyloxycarbonyl-L-proline

Downstream raw materials:

(S)-Proline (R)-menthylamide

L-menthylamine

L-proline

Refernces