Technology Process of C39H42FN7O2
There total 8 articles about C39H42FN7O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trimethylsilyl bromide; methyl-phenyl-thioether; ethane-1,2-dithiol; 3-methyl-phenol; trifluoroacetic acid;
at 0 - 20 ℃;
for 3.5h;
Inert atmosphere;
DOI:10.1016/j.bmcl.2012.04.032
- Guidance literature:
-
Multi-step reaction with 8 steps
1: triethylamine / tetrahydrofuran; water
2: sulfuric acid / tetrahydrofuran
3: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran
4: potassium carbonate; thiophenol / N,N-dimethyl-formamide
5: sodium tris(acetoxy)borohydride / dichloromethane
6: trifluoroacetic acid
7: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 43 h / 0 - 20 °C
8: trimethylsilyl bromide; methyl-phenyl-thioether; ethane-1,2-dithiol; 3-methyl-phenol; trifluoroacetic acid / 3.5 h / 0 - 20 °C / Inert atmosphere
With
trimethylsilyl bromide; methyl-phenyl-thioether; sulfuric acid; sodium tris(acetoxy)borohydride; potassium carbonate; ethane-1,2-dithiol; thiophenol; 3-methyl-phenol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
3: Mitsunobu reaction;
DOI:10.1016/j.bmcl.2012.04.032
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate; thiophenol / N,N-dimethyl-formamide
2: sodium tris(acetoxy)borohydride / dichloromethane
3: trifluoroacetic acid
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 43 h / 0 - 20 °C
5: trimethylsilyl bromide; methyl-phenyl-thioether; ethane-1,2-dithiol; 3-methyl-phenol; trifluoroacetic acid / 3.5 h / 0 - 20 °C / Inert atmosphere
With
trimethylsilyl bromide; methyl-phenyl-thioether; sodium tris(acetoxy)borohydride; potassium carbonate; ethane-1,2-dithiol; thiophenol; 3-methyl-phenol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.04.032
