dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate

Base Information

• Chemical Name: dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate
• CAS No.: 1333431-37-0
• Molecular Formula: C₁₇H₂₀O₅
• Molecular Weight: 304.343
• Mol file: 1333431-37-0.mol

Synonyms:dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate

Chemical Property of dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate

There total 2 articles about dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-bromo-4-methoxy-benzene (104-92-7) + dimethyl 2-(pent-4'-enyl)malonate (93185-10-5) → dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate (1333431-37-0)

Guidance literature:

With potassium phosphate; methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); In N,N-dimethyl-formamide; at 50 ℃; for 24h; diastereoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1039/c9ra08002c

Reference yield: 67.0%

4-chloromethoxybenzene (623-12-1) + dimethyl 2-(pent-4'-enyl)malonate (93185-10-5) → dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate (1333431-37-0)

Guidance literature:

With potassium phosphate; methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); In N,N-dimethyl-formamide; at 80 ℃; for 24h; diastereoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1039/c9ra08002c

Reference yield: 34.0%

dimethyl (2E)-2-(4-methoxybenzylidene)cyclopentane-1,1-dicarboxylate (1333431-37-0) → C17H20O6

Guidance literature:

With sodium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water;

DOI:10.1016/j.tetlet.2011.06.106

upstream raw materials:

4-chloromethoxybenzene

dimethyl 2-(pent-4'-enyl)malonate

1-bromo-4-methoxy-benzene