C₂₄H₂₈N₄O₃S

Base Information

• Chemical Name: C₂₄H₂₈N₄O₃S
• CAS No.: 1569079-17-9
• Molecular Formula: C₂₄H₂₈N₄O₃S
• Molecular Weight: 452.577
• Mol file: 1569079-17-9.mol

Synonyms:C₂₄H₂₈N₄O₃S

Chemical Property of C₂₄H₂₈N₄O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₈N₄O₃S

There total 7 articles about C₂₄H₂₈N₄O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.14%

3-acetylbenzothiophene (1128-05-8) + C14H22N4O3 (1569084-03-2) → C24H28N4O3S (1569079-17-9)

Guidance literature:

With acetic acid; In ethanol; at 60 ℃; for 10h;

Reference yield:

4-amino-3-methoxybenzoic acid ethyl ester (73368-41-9) → C24H28N4O3S (1569079-17-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: potassium carbonate / acetonitrile / 24 h / 100 °C / Autoclave

2.1: water; lithium hydroxide / tetrahydrofuran; methanol / 2 h / 40 °C

3.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 20 °C

3.2: 15 h / 20 °C

4.1: hydrazine hydrate / ethanol / 4 h / 100 °C

5.1: acetic acid / ethanol / 10 h / 60 °C

With hydrazine hydrate; water; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetonitrile;

Reference yield:

3-methoxy-4-nitrobenzoic acid (5081-36-7) → C24H28N4O3S (1569079-17-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: thionyl chloride / 14 h / 60 °C

2.1: palladium on activated charcoal; hydrogen / ethanol / 12 h / 20 °C

3.1: potassium carbonate / acetonitrile / 24 h / 100 °C / Autoclave

4.1: water; lithium hydroxide / tetrahydrofuran; methanol / 2 h / 40 °C

5.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 20 °C

5.2: 15 h / 20 °C

6.1: hydrazine hydrate / ethanol / 4 h / 100 °C

7.1: acetic acid / ethanol / 10 h / 60 °C

With thionyl chloride; hydrazine hydrate; palladium on activated charcoal; water; hydrogen; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetonitrile;

upstream raw materials:

3-acetylbenzothiophene

C₁₄H₂₂N₄O₃

3-methoxy-4-nitrobenzoic acid

Ethyl 3-methoxy-4-nitrobenzoate