(+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine

Base Information

• Chemical Name: (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine
• CAS No.: 1042055-44-6
• Molecular Formula: C₁₈H₂₁N
• Molecular Weight: 251.371

Synonyms:(+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine

Chemical Property of (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine

Chemical Property:

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Technology Process of (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine

There total 4 articles about (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2,2-diphenylhex-5-en-1-amine → 2-methyl-5,5-diphenylpiperidine + (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine (1042055-44-6)

Guidance literature:

With tetrakis(dimethylamido)titanium(IV); In toluene; at 105 ℃; for 96h; Inert atmosphere;

DOI:10.1002/ejoc.200701146

Reference yield:

2,2-diphenyl-6-heptenyl-1-amine → 2-methyl-5,5-diphenylpiperidine + (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine (1042055-44-6)

Guidance literature:

With tetrakis(dimethylamido)titanium(IV); In ⁽²⁾H₈-toluene; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/om3012695

Reference yield:

2,2-diphenylhex-5-en-1-amine → (+/-)-cis-5-methyl-2,2-diphenylcyclopentanamine (1042055-44-6) + C18H21N

Guidance literature:

With tetrakis(dimethylamido)titanium(IV); C₃₃H₂₉NOP₂; In ⁽²⁾H₈-toluene; at 110 ℃; for 24h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/acs.organomet.0c00662

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