diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate

Base Information

Chemical Name:diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate
CAS No.:1402245-45-7
Molecular Formula:C₁₆H₂₂FNO₄
Molecular Weight:311.353
Hs Code.:

Synonyms:diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate

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Technology Process of diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate

There total 2 articles about diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1402245-44-6
diethyl (2R,3S)-2-(N-benzyl-N-methylamino)-3-hydroxysuccinate

: 1402245-45-7
diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate

Guidance literature:: With (bis-(2-methoxyethyl)amino)sulfur trufluoride; In dichloromethane; at 20 ℃; for 15h;
DOI:10.1002/chem.201200071

Reference yield:

: 3291-46-1,3291-47-2,61937-48-2,66647-17-4,74243-85-9,73890-18-3
(2S,3S)-diethyl oxirane-2,3-dicarboxylate

: 103-67-3
benzyl-methyl-amine

: 1402245-45-7
diethyl (2S,3S)-2-(N-benzyl-N-methylamino)-3-fluorosuccinate

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 15 h / Reflux

2: (bis-(2-methoxyethyl)amino)sulfur trufluoride / dichloromethane / 15 h / 20 °C

With (bis-(2-methoxyethyl)amino)sulfur trufluoride; In ethanol; dichloromethane;
DOI:10.1002/chem.201200071