Technology Process of (2S,3S,4R)-2,3,5-tribenzyloxy-4-formyloxypentanal
There total 4 articles about (2S,3S,4R)-2,3,5-tribenzyloxy-4-formyloxypentanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3,4,6-tri-O-benzyl-1,2-O-(1-methoxyethylidene)-α-D-galactopyranose;
With
sulfuric acid;
In
1,4-dioxane;
for 3h;
Heating;
With
sodium periodate;
In
ethanol; water;
at 20 ℃;
for 24h;
DOI:10.1021/jm0605334
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 12 g / Et3N; tetrabutylammonium bromide / 1,2-dichloro-ethane / 20 h / 45 °C
2.1: 65 percent / KOH / toluene / 4 h / Heating
3.1: aq. H2SO4 / dioxane / 3 h / Heating
3.2: 82 percent / sodium metaperiodate / ethanol; H2O / 24 h / 20 °C
With
potassium hydroxide; sulfuric acid; tetrabutylammomium bromide; triethylamine;
In
1,4-dioxane; 1,2-dichloro-ethane; toluene;
DOI:10.1021/jm0605334
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 65 percent / KOH / toluene / 4 h / Heating
2.1: aq. H2SO4 / dioxane / 3 h / Heating
2.2: 82 percent / sodium metaperiodate / ethanol; H2O / 24 h / 20 °C
With
potassium hydroxide; sulfuric acid;
In
1,4-dioxane; toluene;
DOI:10.1021/jm0605334
