C₁₃H₅F₆NO

Base Information

• Chemical Name: C₁₃H₅F₆NO
• CAS No.: 413613-58-8
• Molecular Formula: C₁₃H₅F₆NO
• Molecular Weight: 305.179
• Mol file: 413613-58-8.mol

Synonyms:C₁₃H₅F₆NO

Chemical Property of C₁₃H₅F₆NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₃H₅F₆NO

There total 4 articles about C₁₃H₅F₆NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

→ C13H5F6NO (413613-58-8)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; Pd(OTf)₂(CH₃CN)₄; 1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate; In acetonitrile; at 120 ℃; for 8h; Inert atmosphere;

Reference yield:

N-pentafluorophenylbenzamide (28078-83-3) → C13H5F6NO (413613-58-8)

Guidance literature:

With tetrakis(acetonitrile)palladium bistriflate; 1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate; In 1-methyl-pyrrolidin-2-one; acetonitrile; at 120 ℃; for 8h; regioselective reaction; Inert atmosphere;

DOI:10.1002/anie.201102985

Reference yield:

o-fluoro-benzoic acid (445-29-4) → C13H5F6NO (413613-58-8)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride

2: toluene / 24 h / Reflux

With oxalyl dichloride; In toluene;

DOI:10.1021/acs.joc.6b00083

upstream raw materials:

N-pentafluorophenylbenzamide

o-fluoro-benzoic acid

2,3,4,5,6-pentafluoroaniline

2-Fluorobenzoyl chloride