(4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide

Base Information

• Chemical Name: (4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide
• CAS No.: 139608-76-7
• Molecular Formula: C₁₅H₁₆N₂O₉
• Molecular Weight: 368.3
• Mol file: 139608-76-7.mol

Synonyms:(4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide

Chemical Property of (4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide

There total 1 articles about (4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-Dinitro-benzoic acid (R)-2-((R)-3-carboxy-1-methyl-propyl)-oxiranylmethyl ester → (4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide (139608-76-7) + (4R,5R)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide (139608-77-8)

Guidance literature:

With camphor-10-sulfonic acid; In tetrahydrofuran; for 6h; Yield given. Yields of byproduct given; Heating;

DOI:10.1021/jo00034a017

Reference yield: 82.0%

(4R,5S)-5-(Hydroxymethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide (139608-76-7) → (4R,5R)-5-(Iodomethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide (139608-78-9)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In benzene; for 1.5h; Heating;

DOI:10.1021/jo00034a017

Downstream raw materials:

(4R,5R)-5-(Iodomethyl)-4-methyl-5-<<(3,5-dinitrobenzoyl)oxy>methyl>-5-pentanolide