C₂₈H₂₃FN₆O₃

Base Information

Chemical Name:C₂₈H₂₃FN₆O₃
CAS No.:1354041-66-9
Molecular Formula:C₂₈H₂₃FN₆O₃
Molecular Weight:510.527
Hs Code.:

C<sub>28</sub>H<sub>23</sub>FN<sub>6</sub>O<sub>3</sub>

Synonyms:C₂₈H₂₃FN₆O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₈H₂₃FN₆O₃

Chemical Property:

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Technology Process of C₂₈H₂₃FN₆O₃

There total 4 articles about C₂₈H₂₃FN₆O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1354041-64-7
C₂₈H₂₇FN₆O₃

: 1354041-66-9
C₂₈H₂₃FN₆O₃

Guidance literature:: C₂₈H₂₇FN₆O₃; With ammonium cerium (IV) nitrate; acetic acid; In water; acetonitrile; for 24h;

With sodium hydroxide; In water; ethyl acetate; acetonitrile;

Reference yield:

: 1354041-67-0
ethyl 2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-4-hydroxypyrimidine-5-carboxylate

: 1354041-66-9
C₂₈H₂₃FN₆O₃

Guidance literature:: Multi-step reaction with 4 steps

1: trichlorophosphate / N,N-dimethyl-formamide / toluene / 18 h / 95 °C

2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 24 h / 25 °C

3: diethyl ether; tetrahydrofuran / 4 h / -20 °C / Inert atmosphere

4: ammonium cerium (IV) nitrate; acetic acid / acetonitrile; water / 24 h

With ammonium cerium (IV) nitrate; acetic acid; N-ethyl-N,N-diisopropylamine; trichlorophosphate; N,N-dimethyl-formamide; In tetrahydrofuran; diethyl ether; water; toluene; acetonitrile;

Reference yield:

: 1354041-69-2
ethyl 4-chloro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidine-5-carboxylate

: 1354041-66-9
C₂₈H₂₃FN₆O₃

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 24 h / 25 °C

2: diethyl ether; tetrahydrofuran / 4 h / -20 °C / Inert atmosphere

3: ammonium cerium (IV) nitrate; acetic acid / acetonitrile; water / 24 h

With ammonium cerium (IV) nitrate; acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; water; acetonitrile;