(Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

Base Information

Chemical Name:(Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol
CAS No.:1611459-87-0
Molecular Formula:C₁₆H₂₂O₄
Molecular Weight:278.348
Hs Code.:

Synonyms:(Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

Suppliers and Price of (Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

There total 8 articles about (Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1611459-85-8
ethyl (Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]acrylate

: 1611459-87-0
(Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -50 - -30 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.tetasy.2014.04.002

Reference yield:

: 1611459-96-1
C₁₈H₂₂Cl₃NO₄

: 1611459-87-0
(Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

: 1611459-97-2
N-{(1'R)-1-[(4''R,5''R)-5''-(benzyloxy)-2'',2''-dimethyl-1'',3''-dioxan-4''-yl]allyl}-2,2,2-trichloroacetamide

: 1611459-99-4
N-{(1'S)-1-[(4''R,5''R)-5''-(benzyloxy)-2'',2''-dimethyl-1'',3''-dioxan-4''-yl]allyl}-2,2,2-trichloroacetamide

Guidance literature:: With potassium carbonate; In o-xylene; at 150 ℃; for 2h; Temperature; Sealed tube; Inert atmosphere; Microwave irradiation;
DOI:10.1016/j.tetasy.2014.04.002

Reference yield:

: 1611459-82-5
C₁₈H₁₈O₅

: 1611459-87-0
(Z)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium tetrahydroborate / methanol; dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

2.1: toluene-4-sulfonic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

3.1: potassium carbonate; methanol / 4.42 h / 0 - 20 °C / Inert atmosphere

4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 1 h / Inert atmosphere; Reflux

5.1: sodium hydride / mineral oil; tetrahydrofuran / 0.42 h / -10 - 0 °C / Inert atmosphere

5.2: 1.5 h / 0 °C / Inert atmosphere

6.1: diisobutylaluminium hydride / dichloromethane; toluene / 0.5 h / -50 - -30 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; sodium hydride; diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile; mineral oil; 5.1: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1016/j.tetasy.2014.04.002