C₄₂H₆₈O₁₁Si₂

Base Information

Chemical Name:C₄₂H₆₈O₁₁Si₂
CAS No.:725253-54-3
Molecular Formula:C₄₂H₆₈O₁₁Si₂
Molecular Weight:805.166
Hs Code.:

C<sub>42</sub>H<sub>68</sub>O<sub>11</sub>Si<sub>2</sub>

Synonyms:C₄₂H₆₈O₁₁Si₂

Suppliers and Price of C₄₂H₆₈O₁₁Si₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₂H₆₈O₁₁Si₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₂H₆₈O₁₁Si₂

There total 24 articles about C₄₂H₆₈O₁₁Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 252046-22-3
(2R,3R,4S,4aS,9aS)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-2,3,4,4a,9,9a-hexahydro-6H-pyrano[3,2-b]oxepin

: 725253-54-3
C₄₂H₆₈O₁₁Si₂

Guidance literature:: Multi-step reaction with 19 steps

1.1: AD-mix β; MeSO2NH2 / 2-methyl-propan-2-ol; H2O; various solvent(s) / 0 °C

2.1: CSA / CH₂Cl₂ / 20 °C

3.1: H₂ / Pd/C / ethyl acetate; methanol / 20 °C

4.1: CSA / CH₂Cl₂ / 20 °C

5.1: 92 percent / KOt-Bu; n-Bu₄NI / tetrahydrofuran / 20 °C

6.1: 100 percent / DIBAL-H / CH₂Cl₂ / -78 - 0 °C

7.1: 92 percent / I₂; PPh₃; imidazole / tetrahydrofuran / 20 °C

8.1: 99 percent / NaH / dimethylformamide / 0 - 20 °C

9.1: 9-BBN / tetrahydrofuran / 20 °C

9.2: aq. Cs₂CO₃ / PdCl₂(dppf)*CH₂Cl₂ / tetrahydrofuran; dimethylformamide / 50 °C

10.1: thexylborane / tetrahydrofuran / 0 °C

10.2: 78 percent / aq. NaOH; aq. H₂O₂ / tetrahydrofuran / 20 °C

11.1: TPAP; NMO; 4 Angstroem molecular sieves / CH₂Cl₂ / 20 °C

12.1: TMSCl; LiHMDS; Et₃N / tetrahydrofuran / -78 °C

12.2: Pd(OAc)2 / acetonitrile / 20 °C

13.1: 85 percent / DDQ / CH₂Cl₂ / 20 °C / pH 7

14.1: PPTS / toluene / 50 °C

15.1: Et₃SiH; BF₃*OEt₂ / CH₂Cl₂; acetonitrile / -15 °C

16.1: aq. HCl / tetrahydrofuran; methanol / 50 °C

17.1: Et₃N / CH₂Cl₂ / 20 °C

18.1: lithium di-tert-butylbiphenylide / tetrahydrofuran / -78 °C

19.1: CSA / CH₂Cl₂ / 20 °C

With 1H-imidazole; hydrogenchloride; triethylsilane; 9-borabicyclo[3.3.1]nonane dimer; chloro-trimethyl-silane; N-methyl-2-indolinone; tetrapropylammonium perruthennate; methanesulfonamide; 4 A molecular sieve; lithium di-tert-butylbiphenylide; thexylborane; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; potassium tert-butylate; hydrogen; iodine; pyridinium p-toluenesulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; diisobutylaluminium hydride; 1,4-bis(9-O-dihydroquinidine)phthalazine; triethylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile; tert-butyl alcohol; 9.1: Suzuki-Miyaura coupling / 9.2: Suzuki-Miyaura coupling;
DOI:10.1016/j.tetlet.2004.04.083

Reference yield:

: 725253-39-4
(3aS,4aS,6R,7R,8R,8aS,10aR)-7,8-Bis-benzyloxy-6-benzyloxymethyl-2,2-dimethyl-octahydro-1,3,5,9-tetraoxa-benzo[f]azulene

: 725253-54-3
C₄₂H₆₈O₁₁Si₂

Guidance literature:: Multi-step reaction with 17 steps

1.1: H₂ / Pd/C / ethyl acetate; methanol / 20 °C

2.1: CSA / CH₂Cl₂ / 20 °C

3.1: 92 percent / KOt-Bu; n-Bu₄NI / tetrahydrofuran / 20 °C

4.1: 100 percent / DIBAL-H / CH₂Cl₂ / -78 - 0 °C

5.1: 92 percent / I₂; PPh₃; imidazole / tetrahydrofuran / 20 °C

6.1: 99 percent / NaH / dimethylformamide / 0 - 20 °C

7.1: 9-BBN / tetrahydrofuran / 20 °C

7.2: aq. Cs₂CO₃ / PdCl₂(dppf)*CH₂Cl₂ / tetrahydrofuran; dimethylformamide / 50 °C

8.1: thexylborane / tetrahydrofuran / 0 °C

8.2: 78 percent / aq. NaOH; aq. H₂O₂ / tetrahydrofuran / 20 °C

9.1: TPAP; NMO; 4 Angstroem molecular sieves / CH₂Cl₂ / 20 °C

10.1: TMSCl; LiHMDS; Et₃N / tetrahydrofuran / -78 °C

10.2: Pd(OAc)2 / acetonitrile / 20 °C

11.1: 85 percent / DDQ / CH₂Cl₂ / 20 °C / pH 7

12.1: PPTS / toluene / 50 °C

13.1: Et₃SiH; BF₃*OEt₂ / CH₂Cl₂; acetonitrile / -15 °C

14.1: aq. HCl / tetrahydrofuran; methanol / 50 °C

15.1: Et₃N / CH₂Cl₂ / 20 °C

16.1: lithium di-tert-butylbiphenylide / tetrahydrofuran / -78 °C

17.1: CSA / CH₂Cl₂ / 20 °C

With 1H-imidazole; hydrogenchloride; triethylsilane; 9-borabicyclo[3.3.1]nonane dimer; chloro-trimethyl-silane; N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; lithium di-tert-butylbiphenylide; thexylborane; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; potassium tert-butylate; hydrogen; iodine; pyridinium p-toluenesulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; diisobutylaluminium hydride; triethylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile; 7.1: Suzuki-Miyaura coupling / 7.2: Suzuki-Miyaura coupling;
DOI:10.1016/j.tetlet.2004.04.083

Reference yield:

: (2R,3R,4R,4aS,9aS)-3,4-Bis-benzyloxy-2-benzyloxymethyl-octahydro-1,5-dioxa-benzocycloheptene-7,8-diol

: 725253-54-3
C₄₂H₆₈O₁₁Si₂

Guidance literature:: Multi-step reaction with 18 steps

1.1: CSA / CH₂Cl₂ / 20 °C

2.1: H₂ / Pd/C / ethyl acetate; methanol / 20 °C

3.1: CSA / CH₂Cl₂ / 20 °C

4.1: 92 percent / KOt-Bu; n-Bu₄NI / tetrahydrofuran / 20 °C

5.1: 100 percent / DIBAL-H / CH₂Cl₂ / -78 - 0 °C

6.1: 92 percent / I₂; PPh₃; imidazole / tetrahydrofuran / 20 °C

7.1: 99 percent / NaH / dimethylformamide / 0 - 20 °C

8.1: 9-BBN / tetrahydrofuran / 20 °C

8.2: aq. Cs₂CO₃ / PdCl₂(dppf)*CH₂Cl₂ / tetrahydrofuran; dimethylformamide / 50 °C

9.1: thexylborane / tetrahydrofuran / 0 °C

9.2: 78 percent / aq. NaOH; aq. H₂O₂ / tetrahydrofuran / 20 °C

10.1: TPAP; NMO; 4 Angstroem molecular sieves / CH₂Cl₂ / 20 °C

11.1: TMSCl; LiHMDS; Et₃N / tetrahydrofuran / -78 °C

11.2: Pd(OAc)2 / acetonitrile / 20 °C

12.1: 85 percent / DDQ / CH₂Cl₂ / 20 °C / pH 7

13.1: PPTS / toluene / 50 °C

14.1: Et₃SiH; BF₃*OEt₂ / CH₂Cl₂; acetonitrile / -15 °C

15.1: aq. HCl / tetrahydrofuran; methanol / 50 °C

16.1: Et₃N / CH₂Cl₂ / 20 °C

17.1: lithium di-tert-butylbiphenylide / tetrahydrofuran / -78 °C

18.1: CSA / CH₂Cl₂ / 20 °C

With 1H-imidazole; hydrogenchloride; triethylsilane; 9-borabicyclo[3.3.1]nonane dimer; chloro-trimethyl-silane; N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; lithium di-tert-butylbiphenylide; thexylborane; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; potassium tert-butylate; hydrogen; iodine; pyridinium p-toluenesulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; diisobutylaluminium hydride; triethylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile; 8.1: Suzuki-Miyaura coupling / 8.2: Suzuki-Miyaura coupling;
DOI:10.1016/j.tetlet.2004.04.083