tert-butyloxycarbonyl-alanyl-aminoisobutyryl-alanyl methyl ester

Base Information

Chemical Name:tert-butyloxycarbonyl-alanyl-aminoisobutyryl-alanyl methyl ester
CAS No.:72086-86-3
Molecular Formula:C16H29 N3 O6
Molecular Weight:359.42
Hs Code.:
Mol file:72086-86-3.mol

Synonyms:L-Alanine,N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-2-methylalanyl]-, methyl ester

Suppliers and Price of tert-butyloxycarbonyl-alanyl-aminoisobutyryl-alanyl methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of tert-butyloxycarbonyl-alanyl-aminoisobutyryl-alanyl methyl ester

Chemical Property:

Vapor Pressure:2.15E-09mmHg at 25°C
Boiling Point:480.5°C at 760 mmHg
Flash Point:244.4°C
Density:1.143g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyloxycarbonyl-alanyl-aminoisobutyryl-alanyl methyl ester

There total 8 articles about tert-butyloxycarbonyl-alanyl-aminoisobutyryl-alanyl methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 10065-72-2
L-Alanine methyl ester

: 72095-04-6
Boc-Ala-Aib-OH

: 72086-86-3
N-tert-butyloxycarbonyl-S-alanyl-α-aminoisobutyryl-S-alanine methyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; Ambient temperature;
DOI:10.1016/S0040-4020(01)92061-7

Reference yield: 63.0%

: 2491-20-5
L-alanine methyl ester hydrochloride

: 72095-04-6
Boc-Ala-Aib-OH

: 72086-86-3
N-tert-butyloxycarbonyl-S-alanyl-α-aminoisobutyryl-S-alanine methyl ester

Guidance literature:: With 4-methyl-morpholine; dicyclohexyl-carbodiimide; In dichloromethane; Ambient temperature;
DOI:10.1016/S0040-4020(01)88119-9

Reference yield:

: 15761-38-3
L-N-Boc-Ala

: 72086-86-3
N-tert-butyloxycarbonyl-S-alanyl-α-aminoisobutyryl-S-alanine methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: N-methylmorpholine / tetrahydrofuran / -15 °C

2: tetrahydrofuran / Ambient temperature

3: H₂ / Pd/C / ethanol / 760 Torr

4: N-methylmorpholine / tetrahydrofuran / -15 °C

5: tetrahydrofuran / Ambient temperature

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;