Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester

Base Information

• Chemical Name: Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester
• CAS No.: 188123-35-5
• Molecular Formula: C₁₉H₂₃NO₄
• Molecular Weight: 329.396

Synonyms:Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester

Chemical Property of Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester

There total 3 articles about Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenyllithium (591-51-5) + (1S,2R,6S,7R)-4-Oxo-3-oxa-5-aza-tricyclo[5.2.1.02,6]dec-8-ene-5-carboxylic acid tert-butyl ester (188123-34-4) → Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester (188123-35-5)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 0.166667h;

DOI:10.1016/S0040-4039(96)02402-1

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester (188123-35-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / Et₃N, DMAP / tetrahydrofuran / 1 h / Ambient temperature

2: 95 percent / tetrahydrofuran / 0.17 h / -78 °C

With dmap; triethylamine; In tetrahydrofuran;

DOI:10.1016/S0040-4039(96)02402-1

Reference yield:

(+)-(1S,2R,6S,7R)-3-oxa-5-azatricyclo[5.2.1.02,6]dec-8-en-4-one (139240-75-8) → Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester (188123-35-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / Et₃N, DMAP / tetrahydrofuran / 1 h / Ambient temperature

2: 95 percent / tetrahydrofuran / 0.17 h / -78 °C

With dmap; triethylamine; In tetrahydrofuran;

DOI:10.1016/S0040-4039(96)02402-1

upstream raw materials:

phenyllithium

(1S,2R,6S,7R)-4-Oxo-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-8-ene-5-carboxylic acid tert-butyl ester

di-tert-butyl dicarbonate

(+)-(1S,2R,6S,7R)-3-oxa-5-azatricyclo[5.2.1.0^2,6]dec-8-en-4-one

Downstream raw materials:

Benzoic acid (1R,2R,3R,7S,8S,10R)-2-iodo-5-oxo-4-oxa-6-aza-tricyclo[5.2.1.0^3,8]dec-10-yl ester

Benzoic acid (1S,3S,7S,8S,10R)-5-oxo-4-oxa-6-aza-tricyclo[5.2.1.0^3,8]dec-10-yl ester

(1S,2R,6S,7S,8S)-8-(tert-Butyl-diphenyl-silanyloxy)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one

(1S,2R,6S,7S,8S)-8-(tert-Butyl-diphenyl-silanyloxy)-5-((S)-2-methyl-butyryl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 188123-35-5 Benzoic acid (1S,2R,3S,4R)-3-tert-butoxycarbonylamino-bicyclo[2.2.1]hept-5-en-2-yl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send