3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol

Base Information

• Chemical Name: 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol
• CAS No.: 1268670-64-9
• Molecular Formula: C₆₄H₇₂N₆O₈Si
• Molecular Weight: 1081.4
• Mol file: 1268670-64-9.mol

Synonyms:3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol

Chemical Property of 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol

There total 1 articles about 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(2',3',4'-tri-O-benzyl-6'-O-tosyl-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol (1268670-63-8) → 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol (1268670-64-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 80 ℃; for 14h;

DOI:10.1039/c0cc04127k

Reference yield: 90.0%

3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol (1268670-64-9) → 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol (1268670-65-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 16h;

DOI:10.1039/c0cc04127k

Reference yield: 79.0%

3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol (1268670-64-9) + 3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-8-[4-(2',3',4'-tri-O-benzyl-6'-O-tosyl-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol (1268670-68-3) → C129H137N9O19SSi

Guidance literature:

With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 80 ℃; for 0.25h; Microwave irradiation;

DOI:10.1039/c0cc04127k

upstream raw materials:

3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-1-C-(t-butyldimethylsilyl)-8-[4-(2',3',4'-tri-O-benzyl-6'-O-tosyl-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol

Downstream raw materials:

3,7-anhydro-4,5,6-tri-O-benzyl-1,2,8-trideoxy-8-[4-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1H-1,2,3-triazol-1-yl]-D-glycero-D-gulo-oct-1-ynitol