(E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Base Information

Chemical Name:(E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester
CAS No.:532989-98-3
Molecular Formula:C₂₉H₃₁NO₂
Molecular Weight:425.571
Hs Code.:

Synonyms:(E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Suppliers and Price of (E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

There total 3 articles about (E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 100-51-6,185532-71-2
benzyl alcohol

: 532989-96-1
(3S,4S)-3-Allyl-1-((R)-1-phenyl-ethyl)-4-((E)-styryl)-azetidin-2-one

: 532989-98-3
(E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Guidance literature:: With chloro-trimethyl-silane; In dichloromethane; at 20 ℃; for 48h;
DOI:10.1002/ejoc.200390118

Reference yield:

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 532989-98-3
(E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 0.33 h / 0 °C

2.1: SnCl₄; Et₃N / CH₂Cl₂ / 0.5 h / -78 °C

2.2: 34 percent / CH₂Cl₂ / -78 - 20 °C

3.1: 63 percent / chlorotrimethylsilane / CH₂Cl₂ / 48 h / 20 °C

With chloro-trimethyl-silane; tin(IV) chloride; triethylamine; In dichloromethane;
DOI:10.1002/ejoc.200390118

Reference yield:

: 127759-27-7
cinnamaldehid-(R)-(+)-α-methylbenzylamine derived imine

: 532989-98-3
(E)-(2S,3S)-2-Allyl-5-phenyl-3-((R)-1-phenyl-ethylamino)-pent-4-enoic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: SnCl₄; Et₃N / CH₂Cl₂ / 0.5 h / -78 °C

1.2: 34 percent / CH₂Cl₂ / -78 - 20 °C

2.1: 63 percent / chlorotrimethylsilane / CH₂Cl₂ / 48 h / 20 °C

With chloro-trimethyl-silane; tin(IV) chloride; triethylamine; In dichloromethane;
DOI:10.1002/ejoc.200390118