Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat

Base Information

• Chemical Name: Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat
• CAS No.: 26709-70-6
• Molecular Formula: C₁₈H₂₃NO₃
• Molecular Weight: 301.386
• Mol file: 26709-70-6.mol

Synonyms:Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat

Chemical Property of Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat

Chemical Property:

Purity/Quality:

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Technology Process of Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat

There total 1 articles about Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromoanisole (578-57-4) + ethyl 2-cyano-2-cyclohexylideneacetate (6802-76-2) → Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat (26709-70-6)

Guidance literature:

Multistep reaction; (i) Mg, I₂, (ii) /BRN= 1911577/, CuCl;

DOI:10.1021/jo00800a024

Reference yield:

Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat (26709-70-6) → 1-(2'-Methoxyphenyl)-cyclohexanessigsaeure

Guidance literature:

With potassium hydroxide; In diethylene glycol; at 175 - 185 ℃;

DOI:10.1021/jo00800a024

Reference yield:

Ethyl-α-cyano-1-(2'-Methoxyphenyl)-cyclohexanacetat (26709-70-6) → 2-[1-(2-Methoxy-phenyl)-cyclohexyl]-acetamide

Guidance literature:

With potassium hydroxide; In diethylene glycol; at 175 - 185 ℃;

DOI:10.1021/jo00800a024

upstream raw materials:

2-bromoanisole

ethyl 2-cyano-2-cyclohexylideneacetate