2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole

Base Information

Chemical Name:2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole
CAS No.:1629144-98-4
Molecular Formula:C₁₇H₁₁BrF₃N₃S
Molecular Weight:426.26
Hs Code.:

Synonyms:2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole

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Technology Process of 2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole

There total 2 articles about 2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1629144-77-9
C₁₀H₈F₃N₃S

: 1122-91-4
4-bromo-benzaldehyde

: 1629144-98-4
2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole

Guidance literature:: With acetic acid; In methanol; ethanol; at 80 ℃; for 1h; Inert atmosphere; Schlenk technique;
DOI:10.1002/ejoc.201402129

Reference yield:

: 1629144-56-4
2-phenoxy-5-(4-(trifluoromethyl)phenyl)thiazole

: 1629144-98-4
2-(2-(4-bromobenzylidene)hydrazinyl)-5-(4-(trifluoromethyl)phenyl)thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / dimethyl sulfoxide / 12 h / 100 °C / Inert atmosphere; Schlenk technique

2: acetic acid / ethanol; methanol / 1 h / 80 °C / Inert atmosphere; Schlenk technique

With acetic acid; hydrazine; In methanol; ethanol; dimethyl sulfoxide;
DOI:10.1002/ejoc.201402129