2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid

Base Information

• Chemical Name: 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid
• CAS No.: 106192-43-2
• Molecular Formula: C₁₉H₂₃N₃O₁₀S
• Molecular Weight: 485.472
• Mol file: 106192-43-2.mol

Synonyms:2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid

Chemical Property of 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid

There total 8 articles about 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,3,4-tri-O-acetyl-6-O-(p-tolylsulfonyl)-α-D-galactosyl bromide (13046-90-7) → 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid (106192-43-2)

Guidance literature:

With sodium azide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; In dichloromethane; for 1.5h;

DOI:10.1016/S0008-6215(98)00089-5

Reference yield: 75.0%

1,2,3,4-tetra-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranose (106248-66-2) → 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid (106192-43-2)

Guidance literature:

With trimethylsilylazide; tin(IV) chloride; In dichloromethane; for 20h; Ambient temperature;

Reference yield: 30.0%

acetic anhydride (108-24-7) + α-D-galactopyranosyl azide (106192-39-6) + p-toluenesulfonyl chloride (98-59-9) → 2,3,4-Tri-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranosylazid (106192-43-2)

Guidance literature:

α-D-galactopyranosyl azide; p-toluenesulfonyl chloride; With pyridine; at 0 ℃;

acetic anhydride; at 0 ℃; for 1h;

DOI:10.1021/mp4004817

upstream raw materials:

1,2,3,4-tetra-O-acetyl-6-O-(p-tolylsulfonyl)-β-D-galactopyranose

1-amido-1-deoxygalactopyranose

acetic anhydride

p-toluenesulfonyl chloride

Downstream raw materials:

[¹⁹F]-Gal-RGD