Technology Process of 2,3,4-triphenyl-1-tosyl-1H-pyrrole
There total 3 articles about 2,3,4-triphenyl-1-tosyl-1H-pyrrole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2-[2'-(diphenylphosphanyl)phenyl]-4-phenyl-4,5-dihydrooxazole; nickel(II) acetate tetrahydrate;
In
2,2,2-trifluoroethanol;
at 20 - 80 ℃;
for 24.1667h;
Reagent/catalyst;
Sealed tube;
Inert atmosphere;
DOI:10.1039/c8cc06649c
- Guidance literature:
-
With
bis(1,5-cyclooctadiene)nickel (0); triphenylaluminium; catacxium A;
In
toluene;
at 100 ℃;
for 12h;
DOI:10.1039/b819162j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-d6-formamide / 40 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 20 °C / Cooling with ice
2.2: 20 h / 20 °C
3.1: 2-[2'-(diphenylphosphanyl)phenyl]-4-phenyl-4,5-dihydrooxazole; nickel(II) acetate tetrahydrate / 2,2,2-trifluoroethanol / 24.17 h / 20 - 80 °C / Sealed tube; Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; 2-[2'-(diphenylphosphanyl)phenyl]-4-phenyl-4,5-dihydrooxazole; nickel(II) acetate tetrahydrate; sodium hydride; triethylamine;
In
tetrahydrofuran; 2,2,2-trifluoroethanol; N,N-dimethyl-d6-formamide; mineral oil;
DOI:10.1039/c8cc06649c
