dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate

Base Information

• Chemical Name: dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate
• CAS No.: 138408-16-9
• Molecular Formula: C₂₇H₂₈N₂O₆
• Molecular Weight: 476.529
• Mol file: 138408-16-9.mol

Synonyms:dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate

Chemical Property of dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate

There total 4 articles about dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dibenzyl 1-(1,2,3,4-tetrahydro-7-methoxy-1-oxo-2-naphthyl)-1,2-hydrazinedicarboxylate (138206-93-6) → benzyl (3aRS,9bSR)-N-(2,3,3a,4,5,9b-hexahydro-8-methoxy-2-oxonaphth<2.1-d>oxazol-3-yl)carbamate (138206-90-3) + dibenzyl 1-<(1RS,2RS)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>1,2-hydrazinedicarboxylate (138408-16-9) + dibenzyl 1-<(1RS,2SR)-1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthyl>-1,2-hydrazinedicarboxylate (138206-95-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃; for 1.5h;

Reference yield:

dibenzyl 1-(1,2,3,4-tetrahydro-7-methoxy-1-oxo-2-naphthyl)-1,2-hydrazinedicarboxylate (138206-93-6) → C27H28N2O6 (138206-95-8,138408-16-9)

Guidance literature:

With lithium triethylborohydride; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(00)79428-7

Reference yield:

7-Methoxy-1-tetralone (6836-19-7) → C27H28N2O6 (138206-95-8,138408-16-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) LDA / 1) THF, -78 deg C

2: LiBHEt₃ / tetrahydrofuran / -78 °C

With lithium triethylborohydride; lithium diisopropyl amide; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)79428-7

upstream raw materials:

dibenzyl 1-(1,2,3,4-tetrahydro-7-methoxy-1-oxo-2-naphthyl)-1,2-hydrazinedicarboxylate

7-Methoxy-1-tetralone

dibenzyl azodicarboxylate