(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

Base Information

Chemical Name:(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate
CAS No.:384343-91-3
Molecular Formula:C₂₇H₄₈O₅SSi₂
Molecular Weight:540.912
Hs Code.:

Synonyms:(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

Suppliers and Price of (1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

There total 1 articles about (1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 100-53-8
phenylmethanethiol

: 384343-89-9
(4R,5S)-4,5-bis-(tert-butyldimethylsilanyloxy)-6-oxohex-2-(E)-enoic acid ethyl ester

: 384343-91-3
(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

: (1S,2S,3S,4R,5S)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

: 384343-92-4
(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,5-bis(tert-butyldimethylsiloxy)-4-hydroxycyclopentanecarboxylate

Guidance literature:: With n-butyllithium; In 1,4-dioxane; hexane; at 20 ℃; for 0.5h;
DOI:10.1021/jo016090n

Reference yield: 99.0%

: 384343-91-3
(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

: 384343-96-8
(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4,5-trihydroxycyclopentanecarboxylate

Guidance literature:: With hydrogen fluoride; In acetonitrile; at 0 ℃; for 3h;
DOI:10.1021/jo016090n

Reference yield:

: 384343-91-3
(1R,2R,3S,4R,5R)-ethyl 2-benzylsulfanyl-3,4-bis(tert-butyldimethylsiloxy)-5-hydroxycyclopentanecarboxylate

: 384343-93-5
(3aR,4R,5R,6S,6aS)-ethyl 5-benzylsulfanyl-6-hydroxy-2,2-dimethyltetrahydro-3aH-cyclopenta[1,3]dioxole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / aq. HF / acetonitrile / 3 h / 0 °C

2: 89 percent / p-TsOH*H₂O / 4 h / 20 °C

With hydrogen fluoride; toluene-4-sulfonic acid; In acetonitrile;
DOI:10.1021/jo016090n