(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid

Base Information

• Chemical Name: (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid
• CAS No.: 1236265-43-2
• Molecular Formula: C₂₇H₃₄N₆O₂
• Molecular Weight: 474.606

Synonyms:(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid

Chemical Property of (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid

Chemical Property:

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Technology Process of (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid

There total 1 articles about (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1r,4r)-4-((4-chloro-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid (1236266-18-4) + benzylamine (100-46-9) → (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid (1236265-43-2)

Guidance literature:

In water; acetonitrile; at 80 ℃;

Reference yield: 76.0%

(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid (1236265-43-2) + Sulfathiazole (72-14-0) → (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)-N-(4-(N-thiazol-2-ylsulfamoyl)phenyl)cyclohexanecarboxamide (1236265-50-1)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

Reference yield: 59.0%

(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid (1236265-43-2) + N-ethyl-m-toulidine (102-27-2) → (1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylcyclohexanecarboxamide (1236265-48-7)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

(1r,4r)-4-((4-chloro-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxylic acid

benzylamine

Downstream raw materials:

(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)-N-(4-sulfamoylphenyl)cyclohexanecarboxamide

(1r,4r)-N-(4-(N-acetylsulfamoyl)phenyl)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)cyclohexanecarboxamide

(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)-N-(4-(N-thiazol-2-ylsulfamoyl)phenyl)cyclohexanecarboxamide

(1r,4r)-4-((4-(benzylamino)-6-(2,3-dimethylbenzylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylcyclohexanecarboxamide

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