Chemical Property of (3S)-17-[(E)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Chemical Property:
- Appearance/Colour:White solid
- Vapor Pressure:9.21E-10mmHg at 25°C
- Melting Point:161-170 °C
- Refractive Index:1.504
- Boiling Point:501.1 °C at 760 mmHg
- PKA:15.03±0.70(Predicted)
- Flash Point:219.4 °C
- PSA：20.23000
- Density:0.98 g/cm3
- LogP:7.80080
- Storage Temp.:0-6°C
- Solubility.:chloroform: soluble50 mg/ml
- Water Solubility.:insoluble
- XLogP3:8.6
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:5
- Exact Mass:412.370516150
- Heavy Atom Count:30
- Complexity:674
- Purity/Quality:
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95%-98% *data from raw suppliers
Stigmasterol *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn,
Xi
- Hazard Codes:Xn,Xi
- Statements:
22-38-40-48/20/22-36/37/38-67-36/38-20-63
- Safety Statements:
22-24/25-36/37-36-26
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:CCC(C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
- Isomeric SMILES:CCC(/C=C/C(C)C1CCC2C1(CCC3C2CC=C4C3(CC[C@@H](C4)O)C)C)C(C)C
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Description
Stigmasterol is a kind of plant sterol or phytosterol. It is a kind of steroid derivative containing the hydroxyl group, unsaturated bonds, and alkyl group. It mainly exists in the fats and oils of soybean, Calabar bean, and rape seed as well as some kinds of vegetables, legumes and nuts. It can be used for the manufacture of semisynthetic progesterone which is a valuable human hormone. It can also be used in the biosynthesis of androgen, estrogen, and corticoids. Moreover, it can be used for the manufacture of vitamin D3 and cortisone. As a dietary supplement, it can reduce the cholesterol contained in the human body, thus boosting the health state of our body. Stigmasterol is a natural plant sterol that can be isolated from certain seed oils and herbs, including those used for therapeutic purposes. Dietary consumption of phytosterols, including stigmasterol, may have beneficial health effects in adults, particularly against cancer and ulceration. Alternatively, phytosterols may contribute to inflammation and intestinal failure-associated liver disease in young individuals.
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Uses
Plant sterol, used as a precursor in the synthesis of progesterone. Stigmasterol has been used as a phytosterol compound to test its anti-proliferative property in breast cancer cell culture and its effect on liver X receptor-α (LXRA) activation. It may be used as an internal standard for the quantification of yeast cell wall sterols using gas chromatography–mass spectrometry (GC-MS) analysis, and in the preparation of lipid monolayers.
